Development of a toolkit for early precision immunochromatographic diagnosis
| Autor: | Oleg S. Morenkov, S. V. Dezhurov, P. P. Gladyshev, S. A. Gushchin, A. P. Gushchin, A. A. Vasiliev, D. V. Krylsky |
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| Rok vydání: | 2016 |
| Předmět: |
Spectrometer
Chemistry business.industry 010401 analytical chemistry Nanotechnology 02 engineering and technology STRIPS 021001 nanoscience & nanotechnology Laser 01 natural sciences 0104 chemical sciences Analytical Chemistry law.invention Microprocessor law Control system Colloidal quantum dots Sample collection 0210 nano-technology Luminescence business Computer hardware |
| Zdroj: | Journal of Analytical Chemistry. 71:1063-1068 |
| ISSN: | 1608-3199 1061-9348 |
| DOI: | 10.1134/s1061934816100063 |
| Popis: | A device is developed for automated immunochromatographic assay, designed for one-time tests at the place of occurrence of a disease. The device comprises a turntable platform for up to five strips placed simultaneously, a unit for sample collection and microdosing to a test strip, a detection unit, and a microprocessor control system. A manual, semiautomatic, or automatic operation mode may be selected. Colloidal quantum dots with a luminescence peak from the visible to near-infrared spectral region (600–800 nm) are used as fluorescent labels. A UV-LED or a laser at 365–480 nm can be used as an excitation system; the detection device is a spectrometer with an operation range of 500–800 nm, based on a CCD series of TCD1304DG sensors (Toshiba). RFID tags of samples can re read and the analysis results can be sent to an external computer. The device is made in a plastic case for carrying. |
| Databáze: | OpenAIRE |
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