Convenient synthesis of a marine cyclopentanoid: untenone A

Autor:	Nobuyuki Imai, Takahiro Kunitada, Nobuo Tanaka, Tsutomu Inokuchi, Rikiya Omatsu, Junzo Nokami
Rok vydání:	2010
Předmět:	Chemistry Organic Chemistry Drug Discovery Organic chemistry Alkylation Optically active Biochemistry Kinetic resolution
Zdroj:	Tetrahedron Letters. 51:5525-5528
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2010.07.181
Popis:	(±)-Untenone A, one of the marine cyclopentanoids, has been conveniently synthesized via (±)- cis -1-hexadecylcyclopent-2-en-1,4-diol 9 which has been produced from 1-hexadecylcyclopenta-1,3-diene 6 via photo-oxidation and the following reduction. The key step of the present synthesis is the selective alkylation of cyclopenta-1,3-diene to form 6 . Optically active (−)- and (+)-untenone A have been prepared from (−)- and (+)- 9 , respectively, after enzymatic kinetic resolution of (±)- 9 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dbe167d3738456f69368caf95d0f7f52 https://doi.org/10.1016/j.tetlet.2010.07.181 Zobrazit plný text záznamu Full Text from ScienceDirect