| Autor: |
Dario Bruzzese, Luigi Napoli, Anna Citarella, Ivana Giusy Savino, Gaetano Piccinocchi, Giovanni Sarnelli, L. Vozzella, Enrica Menditto, Simona Cammarota, Rosario Cuomo, S Riegler, Giovanni Arpino |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
European Journal of Clinical Investigation. 42:1068-1078 |
| ISSN: |
0014-2972 |
| DOI: |
10.1111/j.1365-2362.2012.02696.x |
| Popis: |
Background In many countries, the introduction of generic proton pump inhibitors (PPIs) onto thepharmaceutical market increased the phenomenon of therapeutic substitution in acid-related disorders (ARDs).Aim To investigate the treatment of ARDs in an Italian primary care setting from 2005 to 2008 by verifying: (i)dynamics of PPI prescribing; (ii) predictors of PPI switching; and (iii) healthcare resource consumption costs.Methods This was a retrospective cohort study of 102 general practitioners (GPs) who managed an average of150 000 inhabitants in Naples. Multilevel logistic regression was used to assess the potential predictors of bothPPI switching and termination. Primary care costs were expressed as the cost of ARD management per PPI useryear.Results The percentage of PPI users with ARD increased from 5AE5% (2005) to 7AE0% (2008) (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
