Endoscope-compatible confocal microscope using a gradient index-lens system

Autor: Ludger Schnieder, G. F. Buess, T Possner, J Knittel, B Messerschmidt
Rok vydání: 2001
Předmět:
Zdroj: Optics Communications. 188:267-273
ISSN: 0030-4018
Popis: We present an endoscope-compatible confocal laser scanning microscope (CLSM) for medical imaging. A gradient index (GRIN)-lens system projects a magnified image on the distal end of a fiber-optic imaging bundle, which transfers the image to a CLSM situated at the proximal end. As the maximum diameter of the distal optics is 1 mm, application through the accessory channel of a conventional endoscope is possible. A lateral resolution of 3.1 μm and an axial resolution of 16.6 μm is achieved. Confocal images of colonic tissue stained with a fluorescent marker are shown.
Databáze: OpenAIRE