| Popis: |
Haploidentical hematopoietic cell transplantation using CD34+ cells depleted of T lymphocytes by the CliniMACS is a treatment for hematological malignancy. We report on four Mexican children, three with acute lymphocytic leukemia and one with chronic myelocytic leukemia, who was transplanted with 12 × 106 CD34+ stem cells/kg body weight (98% of purity) with a follow-up of years. The engraftment was successful in three of the four children. All showed cytomegalovirus reactivation, and one died because of graft rejection and infectious complication. The risk of infections was a major problem. Pediatr Blood Cancer 2012; 59: 950–952. © 2012 Wiley Periodicals, Inc. |
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