Sleep changes in smokers before, during and 3 months after nicotine withdrawal
| Autor: | Alexander Zober, Andreas Jaehne, Anna-Lisa Schütz, Thomas Unbehaun, Bernd Feige, Verena Uhl, Andrea Rodenbeck, Dieter Riemann, Stefan Cohrs |
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| Rok vydání: | 2014 |
| Předmět: |
Pharmacology
Fagerstrom Test for Nicotine Dependence medicine.diagnostic_test media_common.quotation_subject medicine.medical_treatment Medicine (miscellaneous) Sleep Wake Disorders Polysomnography Abstinence medicine.disease Sleep in non-human animals 3. Good health Nicotine 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Nicotine withdrawal Anesthesia medicine Smoking cessation 030212 general & internal medicine Psychology 030217 neurology & neurosurgery media_common medicine.drug |
| Zdroj: | Addiction Biology. 20:747-755 |
| ISSN: | 1355-6215 |
| DOI: | 10.1111/adb.12151 |
| Popis: | Nicotine may affect sleep by influencing sleep-regulating neurotransmitters. Sleep disorders can increase the risk for depression and substance dependency. To detect the influence of sleep disturbances on the effect of smoking cessation, we investigated polysomnographically (PSG) the sleep of smoking subjects during a period of smoking, during withdrawal and after a period of abstinence from nicotine. Thirty-three smokers (23 male, 10 female, median age 29 years, Fagerstrom Test for Nicotine Dependence score 6.3) were examined during smoking, 24-36 hours after smoking and 3 months after cessation. All subjects had an adaptation night followed by the PSG night. Compared with the smoking state, we found increased arousal index and wake time during nicotine withdrawal. Smokers who later relapsed (11) presented a higher degree of nicotine dependence and more withdrawal symptoms than those who abstained (22) and were characterized by less rapid eye movement (REM) sleep, a longer REM latency as well as by more intense sleep impairments in the subjective sleep rating during the withdrawal. Impairments of sleep during the withdrawal phase may reflect more severe nicotine dependence and may contribute to earlier relapse into smoking behaviours. |
| Databáze: | OpenAIRE |
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