Synthesis, characterization, spectroscopic studies and antimicrobial activity of three new Schiff bases derived from Heterocyclic moiety
| Autor: | Tahar Douadi, Soraya Boukazoula, Farida Sahli, Saifi Issaadi, Salah Chafaa, Mounira Mesbah |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Sulfide 010405 organic chemistry Chemistry Organic Chemistry 010402 general chemistry Condensation reaction Antimicrobial 01 natural sciences 0104 chemical sciences Analytical Chemistry Inorganic Chemistry chemistry.chemical_compound Elemental analysis Thiophene Proton NMR Moiety Organic chemistry Antibacterial activity Spectroscopy |
| Zdroj: | Journal of Molecular Structure. 1151:41-48 |
| ISSN: | 0022-2860 |
| Popis: | Three new Schiff-bases compounds ( I-III ) were synthesized by a condensation reaction in 1:2 M ratios of 4,4′-diaminodiphenyl sulfide and pyrrol/thiophene/furan-2-carboxaldehyde in ethanol. The structural determinations of the Schiff-bases were identified with the help of elemental analysis then confirmed by UV–Vis, FT-IR and 1 H NMR. The products were obtained in excellent yields. On the other hand, the in vitro antibacterial and antifungal activities of the synthesized compounds were investigated using disc diffusion method. Schiff bases synthesized individually exhibited varying degrees of inhibitory effects on the growth of the tested microbial species. |
| Databáze: | OpenAIRE |
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