Biofunctionalization of PEO coatings on titanium implants with inorganic and organic substances
| Autor: | V. R. Mukaeva, Ksenia V. Danilko, Lyudmila V. Parfenova, Andrey Stotskiy, R. G. Farrakhov, N. Rameshbabu, Ruslan Z. Valiev, E.V. Parfenov, A. G. Raab |
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| Rok vydání: | 2020 |
| Předmět: |
Materials science
chemistry.chemical_element 02 engineering and technology Tripeptide engineering.material 010402 general chemistry 01 natural sciences Coating Materials Chemistry technology industry and agriculture Surfaces and Interfaces General Chemistry Plasma electrolytic oxidation 021001 nanoscience & nanotechnology Condensed Matter Physics Electrochemical corrosion 0104 chemical sciences Surfaces Coatings and Films Wear resistance chemistry Chemical engineering engineering Organic component 0210 nano-technology Linker Titanium |
| Zdroj: | Surface and Coatings Technology. 404:126486 |
| ISSN: | 0257-8972 |
| DOI: | 10.1016/j.surfcoat.2020.126486 |
| Popis: | The paper concerns a choice in the biofunctionalization of the coatings produced by plasma electrolytic oxidation: either with inorganic components by introducing Ca-, P- containing compounds into the coating (primarily hydroxyapatite), or with integrin-active organic components (primarily RGD peptides). The following coatings were analyzed: E1 – titania PEO coating, E2 – titania and Ca-, P containing PEO coating, E1 + RGD – titania PEO coating modified with integrin-active RGD (arginine-glycine-aspartic acid) tripeptide sequence anchored to the surface with a bisphosphonate linker. In terms of wear resistance, electrochemical corrosion behavior, and interaction with osteoblast-like cells, coating E1 + RGD seems to be the most promising for the titanium implants. |
| Databáze: | OpenAIRE |
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