Nano drug-delivery systems for management of AIDS: liposomes, dendrimers, gold and silver nanoparticles

Autor:	Fateme Davarani Asl, Marziyeh Mousazadeh, Shirinsadat Taji, Abbas Bahmani, Patricia Khashayar, Mostafa Azimzadeh, Ebrahim Mostafavi
Rok vydání:	2023
Předmět:	Biomedical Engineering Medicine (miscellaneous) General Materials Science Bioengineering Development
Zdroj:	Nanomedicine. 18:279-302
ISSN:	1748-6963 1743-5889
DOI:	10.2217/nnm-2022-0248
Popis:	AIDS causes increasing mortality every year. With advancements in nanomedicine, different nanomaterials (NMs) have been applied to treat AIDS and overcome its limitations. Among different NMs, nanoparticles (NPs) can act as nanocarriers due to their enhanced solubility, sustained release, targeting abilities and facilitation of drug–dose reductions. This review discusses recent advancements in therapeutics for AIDS/HIV using various NMs, mainly focused on three classifications: polymeric, liposomal and inorganic NMs. Polymeric dendrimers, polyethylenimine-NPs, poly(lactic-co-glycolic acid)-NPs, chitosan and the use of liposomal-based delivery systems and inorganic NPs, including gold and silver NPs, are explored. Recent advances, current challenges and future perspectives on the use of these NMs for better management of HIV/AIDS are also discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::db6af20c85bcefd6375103c187bdd352 https://doi.org/10.2217/nnm-2022-0248 Zobrazit plný text záznamu