Adenosquamous carcinoma of the nasal, oral and laryngeal cavities. A clinicopathologic survey of ten cases

Autor: Gordon R. Hennigar, Ronald M. Gerughty, Francis M. Brown
Rok vydání: 1968
Předmět:
Zdroj: Cancer. 22:1140-1155
ISSN: 1097-0142
0008-543X
DOI: 10.1002/1097-0142(196811)22:6<1140::aid-cncr2820220610>3.0.co;2-1
Popis: Ten cases of an unusual form of carcinoma involving the submucosal glands and ducts of the nasal and oral cavities and the larynx were collected and reviewed. The histopathologic features were defined and four distinct component parts were classified: ductal carcinoma in situ, adenocarcinoma, squamous cell carcinoma, and a mixed carcinoma. This tumor was found to be extremely aggressive and highly malignant, with 80% of the cases showing histopathologically proven metastases. The histopathologic features and the clinical behavior of this tumor were sufficiently distinctive to warrant the designation adenosquamous carcinoma. The mode of therapy was evaluated and the treatment of choice appears to be radical surgery. However, the limited number of cases indicates that further collection and subsequent analyses of additional cases must be performed before any definitive conclusions can be drawn.
Databáze: OpenAIRE
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