Pathophysiology, research challenges, and clinical management of smoke inhalation injury
| Autor: | Basil A. Pruitt, Steven E. Wolf, Hiroyuki Sakurai, Perenlei Enkhbaatar, Ronald P. Mlcak, Oscar E. Suman, David N. Herndon |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Smoke Inhalation Injury business.industry Human factors and ergonomics Poison control Consensus criteria 030208 emergency & critical care medicine General Medicine 030204 cardiovascular system & hematology medicine.disease Occupational safety and health Pathophysiology 3. Good health 03 medical and health sciences 0302 clinical medicine Injury prevention medicine Severe burn Medical emergency Intensive care medicine business |
| Zdroj: | The Lancet. 388:1437-1446 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(16)31458-1 |
| Popis: | Summary Smoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. However, relatively little attention has been paid to this devastating condition, and the bulk of research is limited to preclinical basic science studies. Moreover, no worldwide consensus criteria exist for its diagnosis, severity grading, and prognosis. Therapeutic approaches are highly variable depending on the country and burn centre or hospital. In this Series paper, we discuss understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management. |
| Databáze: | OpenAIRE |
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