Popis: |
The specific synthesis of N-alkylated pyridone has attracted considerable attention due to the presence of these units in a wide range of components, both in natural products and in many active pharmaceuticals. Generally, the synthesis of N-alkyl-2-pyridones is feasible by the alkylation of 2-pyridones. In this case, selectively witching the reaction is required to induce N- or O-alkylation. In this communication, we present our results of the synthesis of different N-substituted 2-pyridone using multicomponent reactions (MCRs) methods under microwave radiation conditions. |