One-Pot Synthesis of N-Alkylated 2-Pyridone Derivatives under Microwave Irradiation

Autor: Julio A. Seijas, Zahira Kibou, Noureddine Choukchou-Braham, Ikram Baba Ahmed, Pilar M. Vázquez-Tato
Rok vydání: 2020
Předmět:
Zdroj: The 24th International Electronic Conference on Synthetic Organic Chemistry.
DOI: 10.3390/ecsoc-24-08412
Popis: The specific synthesis of N-alkylated pyridone has attracted considerable attention due to the presence of these units in a wide range of components, both in natural products and in many active pharmaceuticals. Generally, the synthesis of N-alkyl-2-pyridones is feasible by the alkylation of 2-pyridones. In this case, selectively witching the reaction is required to induce N- or O-alkylation. In this communication, we present our results of the synthesis of different N-substituted 2-pyridone using multicomponent reactions (MCRs) methods under microwave radiation conditions.
Databáze: OpenAIRE