Highly Diastereoselective Esterification of Ketenes Generated In Situ from Acyl Chlorides with (R)-Pantolactone Derivatives

Autor:	Takafumi Yamagami, Ryo Kobayashi, Masanori Hatsuda, Masayuki Utsugi, Yasunori Moritani
Rok vydání:	2013
Předmět:	In situ chemistry.chemical_compound Chemistry Stereochemistry Organic Chemistry Organic chemistry Alcohol Physical and Theoretical Chemistry
Zdroj:	European Journal of Organic Chemistry. 2013:7467-7470
ISSN:	1434-193X
DOI:	10.1002/ejoc.201301383
Popis:	Our mechanistic investigations have revealed that Et3N is a key requirement for the highly diastereoselective formation of esters from the corresponding acyl chlorides with (R)-pantolactone via ketene-derived complexes. Furthermore, we have discovered that (R)-N-benzyl-pantolactam is a more effective chiral alcohol than (R)-pantolactone for the esterification of in situ generated ketenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::db34a672d414f3a304d77089c82e2ec7 https://doi.org/10.1002/ejoc.201301383 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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