On the relationship between glycerophosphoglycolipids and lipoteichoic acids of gram-positive bacteria

Autor: Werner Fischer, Raili A. Laine
Rok vydání: 1978
Předmět:
Zdroj: Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 529:250-262
ISSN: 0005-2760
DOI: 10.1016/0005-2760(78)90068-1
Popis: 1. 1. Streptococcus lactis NCDO 712 contains at least three unusually polar glycerophosphoglycolipids. One of them was composed of d -glucose, glycerol, fatty acid ester, and phosphorus in the molar ratio of approx. 2 : 3: 3 : 2. The structure was established as 1,2- di -O- acyl -3-O-[6-(sn- glycero -1- phospho -3-sn- glycero -1- phospho -α- d - glucopyranosyl - → 2)-(6-O- acyl -α- d - glucopyranosyl )]- glycerol . 2. 2. The second glycerophosphoglycolipid was shown to have the same core structure but is lacking the carbohydrate-linked fatty acid. The third glycerophosphoglycolipid is a glycosylated derivative of the first one bearing an α-galactosyl residue at position 2 of the inner glycolipid-linked glycerophosphate moiety. 3. 3. These novel phosphoglycolipids are considered to be the so far missing link between simple glycerophosphoglycolipids and lipoteichoic acids of Grampositive bacteria.
Databáze: OpenAIRE