ChemInform Abstract: Synthesis and Biological Activity of Polygalloyl-Dendrimers as Stable Tannic Acid Mimics

Autor:	Gilbert R. Rooijer, Albert J.J. van den Berg, Roland J. Pieters, S. Bart A. Halkes, Ioannis Vrasidas, Rob M. J. Liskamp
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Natural product Antioxidant Chemistry Dendrimer medicine.medical_treatment Tannic acid medicine Biological activity General Medicine Combinatorial chemistry
Zdroj:	ChemInform. 33
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200235066
Popis:	Inspired by the structure of tannic acid, first- to third-generation dendrimers containing two, four, and eight galloyl moieties were synthesized. Stability, antioxidant activity and collagen cross-linking activity of the natural product and its dendrimer analogues were compared. The experimental results indicate that polygalloyl dendrimers might be used as new lead compounds to improve the long-term healing characteristics of burn wounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dafbee3fbca67ecc2f6072ced51ed8a3 https://doi.org/10.1002/chin.200235066 Zobrazit plný text záznamu Plný text