Prophylaxie anti-D dans l’incompatibilité fœto-maternelle érythrocytaire en Tunisie
| Autor: | R. Achour, I. Ksibi, Kacem S, M. Cheour, W. Bel Haj Ammar, M. Ben Amara, K. Neji |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pregnancy 030219 obstetrics & reproductive medicine Spontaneous miscarriage business.industry Obstetrics Incidence (epidemiology) Retrospective cohort study 030204 cardiovascular system & hematology medicine.disease 03 medical and health sciences 0302 clinical medicine In utero Pediatrics Perinatology and Child Health Medicine Neonatology Young adult business Neonatal resuscitation |
| Zdroj: | Archives de Pédiatrie. 24:942-949 |
| ISSN: | 0929-693X |
| DOI: | 10.1016/j.arcped.2017.07.007 |
| Popis: | Generalization of postnatal prophylaxis using anti-D immunoglobulins decreased the incidence of erythrocyte fetal-maternal incompatibility (EFMI) in the Rhesus system. Few recent studies have investigated the situation of anti-D prophylaxis in Tunisia and its effects on maternal and neonatal health. The aim of this study was therefore to analyze the situation of anti-D prophylaxis in Tunisia to detect defects and propose solutions. We conducted a retrospective descriptive study of IFME cases in the rhesus system in the Department of Medicine and Neonatal Resuscitation of the Tunis Maternity and Neonatology Center (CMNT) during an 8-year period from 1 January 2006 to 31 December 2015. We collected 51 cases of IFME. The prevalence of IFME was 3.4 per 10 000 live births; 41 % of the patients were transferred in utero and they were from the northwest of the country (17 %). The rate of women with a history of at least one spontaneous miscarriage (SCF) was 45 %. In 42 % of the cases, pregnancies were monitored at local clinics. The search for irregular agglutinins (RAI) was performed in 86 % of the women studied. RAI was positive in 97 % of the cases. Anti-D prophylaxis was correctly performed in only 27 % of the cases. The systematic prophylaxis of the third trimester and a systematic Kleihauer test must be combined with postpartum prophylaxis to better identify dysfunctions and improve the application of the recommendations. |
| Databáze: | OpenAIRE |
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