Do pharmacist-led medication reviews in hospitals help reduce hospital readmissions? A systematic review and meta-analysis

Autor: Stéphane Honoré, Pierre Bertault-Peres, Laurent Boyer, Marie-Anne Esteve, Pascal Auquier, Pierre Renaudin
Rok vydání: 2016
Předmět:
Zdroj: British Journal of Clinical Pharmacology. 82:1660-1673
ISSN: 0306-5251
DOI: 10.1111/bcp.13085
Popis: AimsThe aim of this meta-analysis is to examine the impact of a in-hospital pharmacist-led medication reviews in paediatric and adult a patients. a MethodsRelevant studies were identified from the Medline and Cochrane a Library databases. Studies were included if they met the following a criteria (without any language or date restrictions): design: randomized a controlled trial; intervention: in-hospital pharmacist-led medication a review (experimental group) vs. usual care (control group); a participants: paediatric or adult population. The primary outcome was a all-cause readmissions and/or emergency department (ED) visits at a different time points. The secondary outcomes were all-cause a readmissions, all-cause ED visits, drug-related readmissions, mortality, a length of hospital stay, adherence and quality of life. We calculated a the relative risk (RR) or mean differences (MD) with 95% confidence a intervals (CIs) for each study. We used fixed and/or random effects a models. Heterogeneity was assessed using the I-2 statistic. a ResultsWe systematically reviewed 19 randomized controlled trials (4805 a participants). The readmission rates did not differ between the a experimental group and the control group (RR=0.97, 95% CI 0.89; 1.05, a p=0.470). The secondary outcomes did not differ between the two groups, a except for in drug-related readmissions, which were lower in the a experimental group (RR=0.25, 95% CI 0.14; 0.45, p
Databáze: OpenAIRE
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