Isolation and characterization of triterpenoid saponins from leaves of Aralia nudicaulis L
| Autor: | Jean Legault, Quentin Lion, Serge Lavoie, André Pichette, Julie Pierra, Diamondra Raminoson, Vakhtang Mshvildadze |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Chemistry Stereochemistry Glycoside Plant Science Isolation (microbiology) 01 natural sciences Biochemistry Aralia nudicaulis 0104 chemical sciences 010404 medicinal & biomolecular chemistry Triterpenoid No production Agronomy and Crop Science Two-dimensional nuclear magnetic resonance spectroscopy Biotechnology |
| Zdroj: | Phytochemistry Letters. 43:184-189 |
| ISSN: | 1874-3900 |
| Popis: | Three new oleanolic glycosides (1–3), along with seven known saponins from various plants (4–10) were isolated for the first time from the leaves of Aralia nudicaulis. Their structures were elucidated on the basis of spectroscopic evidence, including 1D and 2D NMR, and HRESIMS. Nudicauloside A and B (1–2) have shown moderate anti-inflammatory activity, as demonstrated by inhibition of LPS-induced NO production in raw 264.7 murine macrophages (IC50 = 74–101 μM). |
| Databáze: | OpenAIRE |
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