Preparation of Acrylophenones and 2-Alkyl Indanones Utilizing Hexamethylenetetramine as an Inexpensive Mannich Reagent

Autor: Arnold Ybarra, Apurba Bhattacharya, Brigitte E. Segmuller
Rok vydání: 1996
Předmět:
Zdroj: Synthetic Communications. 26:1775-1784
ISSN: 1532-2432
0039-7911
DOI: 10.1080/00397919608002617
Popis: Hexamethylenetetramine/acetic anhydride-promoted α-methylenation of aryl alkyl ketones followed by acid-catalyzed cyclization of the resulting acrylophenones produce 2-alkyl indanones in excellent yields.
Databáze: OpenAIRE