Synthesis of β-aminosulfonopeptides activated through selective N-nitration of a taurine amide unit

Autor:	Seunguk Paik, Emil H. White
Rok vydání:	1996
Předmět:	chemistry.chemical_classification Taurine Stereochemistry medicine.drug_class Organic Chemistry Carboxamide Biochemistry Amino acid Sulfonamide chemistry.chemical_compound chemistry Nitration Amide Drug Discovery medicine
Zdroj:	Tetrahedron Letters. 37:4663-4666
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00903-3
Popis:	β-Sulfonopeptides bearing a taurine in place of a penultimate amino acid unit were designed and synthesized as inhibitors of D-alanyl-D-alanine transpeptidases; N-nitration of the sulfonamide bond in the presence of multiple carboxamide groups was selectively accomplished through use of NO 2 BF 4 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::da98fd85e98b4990e98985bc06d70293 https://doi.org/10.1016/0040-4039(96)00903-3 Zobrazit plný text záznamu Full Text from ScienceDirect