The Preparation of Substituted 1(2H)-Isoquinolinones from Polylithiated 2-(2-Methylphenyl)Hydrazinecarboxylic Acid Esters

Autor: Margaret A. Hines, Madlene U. Koller, Charles F. Beam, Richard A. Taylor, Rene J. Lachiocotte, Cynthia L. Mazat Griffith, Cameron A. Church
Rok vydání: 1996
Předmět:
Zdroj: Synthetic Communications. 26:1763-1774
ISSN: 1532-2432
0039-7911
Popis: 2-(2-Methylphenyl)hydrazinecarboxylic acid esters were metalated with excess lithium diisopropylamide, and the resulting polyanion-type intermediates were condensed with aromatic esters followed by acid cyclization to the 3-substituted- 1 (2H)-isoquinolinones (isocarbostyrils).
Databáze: OpenAIRE