The Preparation of Substituted 1(2H)-Isoquinolinones from Polylithiated 2-(2-Methylphenyl)Hydrazinecarboxylic Acid Esters
Autor: | Margaret A. Hines, Madlene U. Koller, Charles F. Beam, Richard A. Taylor, Rene J. Lachiocotte, Cynthia L. Mazat Griffith, Cameron A. Church |
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Rok vydání: | 1996 |
Předmět: | |
Zdroj: | Synthetic Communications. 26:1763-1774 |
ISSN: | 1532-2432 0039-7911 |
Popis: | 2-(2-Methylphenyl)hydrazinecarboxylic acid esters were metalated with excess lithium diisopropylamide, and the resulting polyanion-type intermediates were condensed with aromatic esters followed by acid cyclization to the 3-substituted- 1 (2H)-isoquinolinones (isocarbostyrils). |
Databáze: | OpenAIRE |
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