Maternal and Perinatal Outcome of Pregnancy with Hepatitis E Infection

Autor:	Nira Singh Shrestha, Sanjaya K. Shrestha, Kasturi Malla, Laxmi Bikram Thapa, Asha Singh
Rok vydání:	2011
Předmět:	Hepatitis Pediatrics medicine.medical_specialty Pregnancy business.industry Perinatal mortality Obstetrics and Gynecology Perinatal outcome medicine.disease medicine.disease_cause Hepatitis E Hepatitis E virus medicine Still birth business Hepatitis E virus infection
Zdroj:	Journal of South Asian Federation of Obstetrics and Gynaecology. 3:17-20
ISSN:	0975-1920 0974-8938
DOI:	10.5005/jp-journals-10006-1115
Popis:	Objective To see the prevalence of HEV infection in the cases of acute hepatitis among pregnant women, and maternal and perinatal outcome of pregnancy complicated by HEV infection. Methods This was a descriptive study done at two tertiary care hospital in Kathmandu, Nepal between July 2006 and June 2007. Women presenting with acute hepatitis were tested for HEV using commercial rapid HEV test kit (assure HEV IgM Rapid test by MP diagnostics). Pregnant women, who tested positive for HEV, were enrolled as study group. Maternal and perinatal outcome of these women were analyzed. Results Ninety-three pregnant women with acute hepatitis due to HEV were admitted during the study period. Of these 93 cases, acute liver failure occurred in 24 (25.8%), acute renal failure in eight (8.6%) and maternal mortality occurred in 18 (19.35 %). Five women (5.4%) had miscarriage and 79 delivered (53 preterm and 26 term). Pregnancy continued in nine. Perinatal mortality occurred in 16 (20.2%) of which nine were still birth and seven neonatal deaths. Conclusion Hepatitis E virus infection is a major cause of acute hepatitis in pregnant women with adverse maternal and perinatal outcome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::da78a78119bc811e4b10b2e35c36a6b6 https://doi.org/10.5005/jp-journals-10006-1115 Zobrazit plný text záznamu