Probes Containing Gamma Radiation Detectors For In Vivo Tumor Detection And Imaging

Autor: N.E. Hartsough, T. S. Hickernell, Harrison H. Barrett, H.B. Barber, James M. Woolfenden, D. P. Kwo
Rok vydání: 1989
Předmět:
Zdroj: SPIE Proceedings.
ISSN: 0277-786X
DOI: 10.1117/12.952174
Popis: External gamma-camera imaging using tumor-seeking radiotracers has been shown to be insensitive in the task of identifying small tumors situated deep inside the body. Our approach is to use probes containing miniature radiation detectors which, when maneuvered close to a tumor, overcome the limitations of external imaging. We discuss our results from using such probes for bronchoscopic and surgical tumor detection. A limitation that prevents the detection of small tumors with these probes is the spatial variation of the background count rate due to distant background sources of high radiotracer uptake. We present two techniques for solving this problem geometric background subtraction and imaging.
Databáze: OpenAIRE