Effect of Surgical Complications on Quality of Life after Thoracoscopic Lobectomy for Lung Cancer

Autor:	Jeffrey A. Johnson, James D. Kutsogiannias, Sayf Gazala, Eric L.R. Bédard
Rok vydání:	2014
Předmět:	medicine.medical_specialty Lung cancer surgery business.industry medicine.disease Surgery Quality of life Cohort Global health medicine Stage (cooking) Lung cancer business Generalized estimating equation Cohort study
Zdroj:	World Journal of Cardiovascular Surgery. :25-34
ISSN:	2164-3210 2164-3202
Popis:	Background: Surgical resection is the main treatment for early stage lung cancer; the benefits of surgery, however, need to be weighed against possible complications and patients’ quality of life. Methods: We performed a cohort study following patients after video assisted thoracoscopic lobectomy at our tertiary care center. Before surgery, health related quality of life was assessed using the SF-36, the QLQ30, QLQ13 and EQ5D questionnaires. Post-operatively health related quality of life was assessed at regular intervals (2, 4, 8 and 12 weeks). A research team assessed post-operative complications on a daily basis during the patients’ hospital stay. Based on the Clavien classification system, the cohort was classified as experiencing high-grade (i.e., grade III or IV) complications or not. Changes in quality of life scores over the follow-up period were compared using linear regression with generalized estimating equations. Results: Between March and September 2011, 44 eligible patients were recruited into the study. The mean age was 65 (SD 8.7) years; 55% were male. The majority (n = 31; 71%) had no or low-grade complications. Patients experiencing high-grade complications reported significantly worse outcomes in the following domains of the SF-36: Global Health, Vitality, and Physical Functioning (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::da73300305dd301f6dd3d16bf2d7f254 https://doi.org/10.4236/wjcs.2014.43005 Zobrazit plný text záznamu