Enrichment ofBifidobacterium longumsubsp.infantisATCC 15697 within the human gut microbiota using alginate-poly-l -lysine-alginate microencapsulation oral delivery system: anin vitroanalysis using a computer-controlled dynamic human gastrointestinal model
| Autor: | Laetitia Rodes, Meenakshi Malhotra, Arghya Paul, Daniel Marinescu, Shyamali Saha, Satya Prakash, Catherine Tomaro-Duchesneau, Imen Kahouli, Wei Shao |
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| Rok vydání: | 2013 |
| Předmět: |
Bifidobacterium longum
biology Chemistry Organic Chemistry Pharmaceutical Science Bioengineering Gut flora biology.organism_classification Microbiology law.invention In vitro analysis Probiotic Colloid and Surface Chemistry Human gut law Gastric acid Alginate-poly-L-lysine Food science Delivery system Physical and Theoretical Chemistry |
| Zdroj: | Journal of Microencapsulation. 31:230-238 |
| ISSN: | 1464-5246 0265-2048 |
| Popis: | This study evaluates alginate-poly-l-lysine-alginate Bifidobacterium longum subsp. infantis ATCC 15697-loaded microcapsules to enrich the human gut microbiota. The cell survival of alginate-poly-l-lysine-alginate microencapsulated B. infantis ATCC 15697 in gastric acid, bile, and through human gastrointestinal transit was investigated, as well as the formulation’s effect on the gut microbiota. Results show that microencapsulation increases B. infantis ATCC 15697 cell survival at pH1.0 (33.54 ± 2.80% versus |
| Databáze: | OpenAIRE |
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