Bromodimethylsulfonium bromide: an efficient catalyst for one-pot synthesis of 4-phenacylidene flavene derivatives

Autor: Deb K. Das, S. Bhattacharjee, Abu T. Khan
Rok vydání: 2015
Předmět:
Zdroj: Tetrahedron Letters. 56:2412-2415
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2015.03.047
Popis: The synthesis of 4-phenacylidene flavenes (3) was accomplished by a one-pot pseudo three-component condensation reaction between salicylaldehydes and acetophenones in the presence of 20 mol % of bromodimethylsulfonium bromide (BDMS) in acetonitrile at room temperature. The attractive features of this protocol are: use of organo-catalyst BDMS, simple reaction procedure, high bond-forming efficiency, good yields, and environmentally benign reaction conditions.
Databáze: OpenAIRE