Global and pediatric aspects of Zika virus infection
| Autor: | Tatyana A. Kaplina, Dmitry O. Ivanov, Jean-Claude Hakizimana, Vladimir N. Timchenko, Valentina V Malinovskaya |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Pediatrics Interferon inducer biology business.industry Myelitis Meningoencephalitis medicine.disease biology.organism_classification Virology Zika virus 03 medical and health sciences 0302 clinical medicine Epidemiology Maculopapular rash medicine Etiology 030212 general & internal medicine medicine.symptom business Encephalitis |
| Zdroj: | Pediatrician (St. Petersburg). 7:129-134 |
| ISSN: | 2587-6252 2079-7850 |
| Popis: | This article presents the results of data analysis or references on etiology, epidemiology, pathogenesis, clinical features, therapy and prophylaxis of Zika virus infection. The article presents the results of the literature analysis of the data on the etiology, epidemiology, pathogenesis, clinical presentation, treatment and prevention of Zika virus infection. Currently Zika fever is common in tropical climates (Uganda, Brazil, Haiti, Colombia, Ecuador, El Salvador, Venezuela, Jamaica, Thailand, etc.). However, a large number of travelers and areolas mosquito habitat Αedes kind of make this a global problem. Acquired Zika virus infection usually occurs in mild and/or moderate forms. The development of severe forms occurs mainly in people with a weakened immune system or autoimmune diseases. Patients affected with Zika virus may develop neurological complications such as encephalitis, myelitis, optic neuritis, meningoencephalitis, Guillain-Barre syndrome. Transplacental and sexual transmissions contribute to an increase in the number of cases among children, including newborns. Zika congenital infection is characterized with brain damage, hearing and sight. Acquired Zika fever in children is accompanied by the presence of the following syndromes: subfebrile fever, mild intoxication, maculopapular rash with a landmark distribution, arthralgia, myalgia, photophobia and conjunctivitis, diarrhea rarely observed. In the laboratory diagnosis are used virological, molecular biological and serological methods. There are no specific prophylactic methods.To treat Zika virus infection, may be used recombinant human inteferona α2β and interferon inducers. |
| Databáze: | OpenAIRE |
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