Hyperbaric Oxygen in Combination with Other Therapies for Idiopathic Sudden Sensorineural Hearing Loss

Autor: Nobuaki Hiraki, Gunji Nagatani, Tetsuro Wakasugi, Koichi Hashida, Tsuyoshi Udaka, Hideaki Suzuki, Takanori Mori
Rok vydání: 2008
Předmět:
Zdroj: Practica Oto-Rhino-Laryngologica. 101:663-667
ISSN: 1884-4545
0032-6313
Popis: Hyperbaric oxygen (HBO) therapy combined with steroid administration is an effective treatment for idiopathic sudden sensorineural hearing loss (ISSNHL), but is sometimes unfeasible for patients with underlying diseases, particularly for those with steroid-intolerance. We conducted a controlled retrospective analysis of patients with ISSNHL who received HBO in combination with stellate ganglion block (SGB), prostaglandin (PG) E1, or steroid therapy in order to identify possible alternative regimens.Three hundred and six consecutive patients with ISSNHL (average hearing levels of 5 frequencies (250-4000Hz)≥40dB; time from the onset of hearing loss to the start of treatment ≤30 days) were enrolled. One hundred and ten, 95, and 101 patients underwent SGB+HBO (SGB group), PGE1+HBO (PG group), and steroid+HBO therapy (steroid group), respectively. Hearing recovery was evaluated by grade assessment, by hearing gain, and by hearing improvement rate compared to the unaffected contralateral ear.The overall hearing outcome did not differ among the three groups. In patients with initial hearing levels
Databáze: OpenAIRE