Autor:	R. Santangelo, V. G. Nicoletti, L. Torrisi, P. Dell'Albani, A. M. Giuffrida Stella
Rok vydání:	2003
Předmět:	Regulation of gene expression PIM1 JAK-STAT signaling pathway General Medicine Biology Biochemistry stat Cell biology Cellular and Molecular Neuroscience Hes3 signaling axis Cell surface receptor Cancer research Signal transduction STAT4
Zdroj:	Neurochemical Research. 28:53-64
ISSN:	0364-3190
DOI:	10.1023/a:1021644027850
Popis:	Over the last 20 years the JAK/STAT signal transduction pathway has been extensively studied. An enormous amount of data on different cell signal transduction pathways is now available. The JAK/STAT signal transduction pathway is one of the intracellular signaling pathways activated by cytokines and growth factors that was first studied in the hematopoietic system, but recent data demonstrate that this signal transduction is also greatly utilized by other systems. The JAK/STAT pathway is a signaling cascade that links the activation of specific cell membrane receptors to nuclear gene expression. This review is focused on the role of JAK/STAT signal transduction pathway activation in the central nervous system (CNS).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d9f1c28c5408dd7915aea35860aca700 https://doi.org/10.1023/a:1021644027850 Zobrazit plný text záznamu Full text from SpringerLink