| Autor: |
Ainara García-Marijuan, Luisa Carrillo, Jose L. Vicario, Iratxe Ugarriza, Silvia Reboredo, Efraim Reyes, Uxue Uria |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Organic Chemistry Frontiers. 5:933-942 |
| ISSN: |
2052-4129 |
| DOI: |
10.1039/c7qo00793k |
| Popis: |
An efficient and easy protocol for promoting a C → N acyl transfer reaction in diverse enantiopure densely substituted pyrrolidine 2,2-dicarboxylates was performed, yielding the corresponding proline ester derivatives with yields in the range of 68–99% and total diastereoselection (dr > 95 : 5 in all cases). The substitution patterns both at C-3 and C-5 present in starting pyrrolidines as well as the viability of presenting different alkoxycarbonyl moieties have been evaluated observing good reaction performance in all cases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
