The unpredictable erythrocyte deformability alteration in some hematological disorders: How the classification of primary hyperviscosity syndromes could change

Autor:	G. Caimi, M. Carlisi
Rok vydání:	2023
Předmět:	Physiology Physiology (medical) Hematology Cardiology and Cardiovascular Medicine
Zdroj:	Clinical Hemorheology and Microcirculation. 83:341-349
ISSN:	1875-8622 1386-0291
DOI:	10.3233/ch-221549
Popis:	According to Wells classification, it is possible to distinguish the primary hyperviscosity syndromes in polycythemic, sclerocythemic and sieric and/or plasmatic. In polycythemia vera, multiple myeloma, Waldenström’s macroglobulinemia, and monoclonal gammopathy of undetermined significance, we have observed an unexpected behaviour of the erythrocyte deformability. This data highlights that the hemorheological alteration present in polycythemia vera has not been related to the increase of RBC mass only, as well as that present in plasmacellular dyscrasias has not been attributable to the increase of plasma viscosity only. The aim of this paper is to suggest some starting points for an accurate reflection, emphasizing the need of a revision of the current classification of primary hyperviscosity syndromes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d9d4bd97d8a2903ebd611c45a7636975 https://doi.org/10.3233/ch-221549 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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