A novel approach to the indoloquinoline alkaloids cryptotackieine and cryptosanguinolentine by application of cyclization of o-vinylsubstituted arylheterocumulenes

Autor:	Santiago Delgado, Pilar M. Fresneda, Pedro Molina
Rok vydání:	2001
Předmět:	chemistry.chemical_compound chemistry Insertion reaction Microwave heating Intramolecular force Organic Chemistry Drug Discovery Polymer chemistry Trimethylphosphine Microwave irradiation Biochemistry Isocyanate Derivative (chemistry)
Zdroj:	Tetrahedron. 57:6197-6202
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)00597-x
Popis:	1-Methyl-3-( o -azidophenyl)quinoline-2-one prepared by cyclization of the corresponding o -vinylsubstituted isocyanate under microwave irradiation is directly converted into cryptotackieine 1 by an intramolecular aza-Wittig reaction with trimethylphosphine; alternatively heating followed by reduction of the resulting indoloquinoline derivative provided cryptosanguinolentine 2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d99c85cb4150ca743fd876a1956d08f0 https://doi.org/10.1016/s0040-4020(01)00597-x Zobrazit plný text záznamu Full Text from ScienceDirect