Controversies in the Management of Community-Acquired Pneumonia
| Autor: | Raja Jagadeesan, Kanal Singh |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Guideline adherence business.industry Standard treatment 030106 microbiology General Medicine Disease Serious infection medicine.disease Procalcitonin 03 medical and health sciences Pneumonia 0302 clinical medicine Community-acquired pneumonia medicine 030212 general & internal medicine Risks and benefits business Intensive care medicine |
| Zdroj: | Current Emergency and Hospital Medicine Reports. 4:126-135 |
| ISSN: | 2167-4884 |
| DOI: | 10.1007/s40138-016-0107-0 |
| Popis: | Community-acquired pneumonia remains a common and serious infection, contributing to significant morbidity and mortality. Despite a more standardized approach towards management of this disease, several key uncertainties still remain. In this narrative review we examine the latest evidence to investigate what we identified as three of the most clinically relevant controversies. Novel tests including procalcitonin and molecular assays for respiratory viruses may facilitate earlier diagnosis, but their routine use and clinical utility are unclear. In addition, determining an optimal empiric antibiotic regimen continues to be a challenge. Lastly, systemic corticosteroids have been theorized as possible adjuncts to standard treatment, but their risks and benefits need to be more fully explored. Recent evidence lends some support to the use of newer diagnostic assays and corticosteroids in the management of community-acquired pneumonia. Additionally, empiric antibiotic selection should be guided by a combination of expert guideline adherence, local epidemiologic trends, and clinical judgement. |
| Databáze: | OpenAIRE |
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