Comparative Rheomechanical and Adhesive Properties of Two Hydrocolloid Dressings: Dependence on the Degree of Hydration
| Autor: | M. Bertoni, Silvia Rossi, M. E. Aulton, Franca Ferrari, Carla Caramella, Maria Cristina Bonferoni, M. J. Waring |
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| Rok vydání: | 1996 |
| Předmět: |
Pharmacology
Materials science Organic Chemistry Pharmaceutical Science Excipient Viscoelasticity Comparative evaluation Degree (temperature) chemistry.chemical_compound chemistry Rheology Drug Discovery Polymer chemistry medicine Adhesive Composite material Saturation (chemistry) Polyurethane medicine.drug |
| Zdroj: | Drug Development and Industrial Pharmacy. 22:1223-1230 |
| ISSN: | 1520-5762 0363-9045 |
| DOI: | 10.3109/03639049609063241 |
| Popis: | Hydration is believed to modify the mechanical properties (resistance to stress) and the rheological (viscoelastic) properties of hydrocolloid dressings. Rheomechanical properties in turn influence adhesional properties. In this work the relationships between the degree of hydration and the rheomechanical and the adhesive properties of two different commercial dressings (regular and nondispersive) were investigated. The two dressings showed different hydration characteristics. The regular dressing takes up water rapidly and tends to reach saturation after 12 hr. As the dressing swells and loses its integrity there is an accompanying reduction of both rheomechanical and adhesive properties. The nondispersive dressing exhibits a linear water uptake profile over extended periods of hydration up to 4 days. It does not swell and its rheomechanical and adhesive properties remain unchanged after hydration, The comparative evaluation of the results obtained with the various methods points to the relevance... |
| Databáze: | OpenAIRE |
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