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Introduction Asthma exacerbations are an important cause of emergency department visits. The 30-day readmission rate, which is a marker of asthma severity, remains substantial. The aim of our study was to assess demographic and clinical factors associated with early asthma readmissions. Methods We used data from the Nationwide Readmission Database (NRD). We identified adults (≥18 years) with index hospitalizations for an acute asthma exacerbation and calculated odds ratio (ORs) of various factors with 30-day readmission. As the database contains de-identified patient data, IRB approval was not required. Results In 2014, we identified 162,142 (estimated total of 352,750 in the US) index discharges for asthma exacerbation, 4,991 (estimated 10,808, ∼ 3%) of whom were readmitted within 30 days. On multivariate analysis, nondependent abuse or dependence on prescription medications (opiates, anxiolytics, sedatives, hypnotics) were associated with the highest odds of early readmission (OR 1.56, 95 % CI 1.34–1.80, p Conclusions Prescription opiates and anxiolytics have been previously identified as predictors for early hospital readmission. Steroid use likely indicates baseline disease severity, with subsequent higher readmissions. Mounting evidence demonstrates that obesity and GERD adversely affect asthma inception, severity, and response to therapy. It is important to identify high-risk features for readmission in order to target preventative interventions to those at highest risk. Factors Associated with Early Readmission in Acute Asthma Exacerbation on Uni- and Multi-variate Analyses Figure 1. Factors associated with increased Early (30-day) Readmission in Hospitalizations with Acute Exacerbation of Asthma. |
