| Popis: |
The presented investigations were carried out in order to detect environmental pollutants using the HT29, HepG2 and A549 cultured human cells as biological sensors of toxicity. We measured the growth rate inhibition and the expression level of stress proteins after exposure to cadmium, nickel, chromium, ethanol, 1-propanol, benzene, toluene, xylene, dichlorobenzene and trichlorobenzenes. Threshold concentrations were determined for selected pollutants and significance as well as reliability of the results were discussed. New perspectives for developing improved biodetectors are reported. |
