Papain-catalyzed polymerization of amino acids in low water organic solvents

Autor:	Anne Ferjancic, Antoine Puigserver, Hubert Gaertner
Rok vydání:	1991
Předmět:	chemistry.chemical_classification Bioengineering Phenylalanine General Medicine Applied Microbiology and Biotechnology Toluene Oligomer Enzyme catalysis Amino acid chemistry.chemical_compound Papain chemistry Polymerization Amide Organic chemistry Biotechnology
Zdroj:	Biotechnology Letters. 13:161-166
ISSN:	1573-6776 0141-5492
Popis:	Polyethylene glycol-modified papain catalyzed the oligomerization of amino acid amides in toluene. The water content of the organic solvent was a critical factor determining the extent of polymerization. Under optimized conditions, lysine and phenylalanine oligomers containing up to 10 residues were obtained. In sharp contrast to what is observed in aqueous media, hydrophilic and basic amino acid derivatives resulted in higher reaction yields than hydrophobic amino acid derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d96a185529c657aceb0547bef7016283 https://doi.org/10.1007/bf01025811 Zobrazit plný text záznamu Full text from SpringerLink