Aza-Michael reaction as an efficient method for the synthesis of first representatives of β-azahetaryl-β-diphenylphosphorylalkanones

Autor:	E. I. Goryunov, Polina S. Protopopova, M. A. Galkina, Konstantin A. Kochetkov, I. B. Goryunova, Valery K. Brel, A. B. Uryupin, T. T. Vasil'eva, G. V. Bodrin, A. E. Saifutiarova, Asmik A. Ambartsumyan
Rok vydání:	2016
Předmět:	Bicyclic molecule 010405 organic chemistry chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Nitrogen 0104 chemical sciences Adduct Catalysis NMR spectra database chemistry.chemical_compound chemistry Michael reaction Imidazole Organic chemistry
Zdroj:	Russian Chemical Bulletin. 65:1855-1858
ISSN:	1573-9171 1066-5285
Popis:	Aza-Michael reaction of (E)-4-(diphenylphosphoryl)but-3-en-2-one (1) with a number of mono-and bicyclic nitrogen heterocycles proceeds regioselectively in the absence of catalysts with the formation of corresponding β-azahetaryl β-diphenylphosphoryl ketones; in the case of imidazole, the presence of chiral organic catalysts allows one to increase the yields of the adducts and to obtain them in enantiomerically enriched form.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d966a8725da2a9bac8dede7dd3c47dcd https://doi.org/10.1007/s11172-016-1520-y Zobrazit plný text záznamu Full text from SpringerLink