Synthesis of the sesquiterpenoid trichodiene using a free radical fragmentation approach

Autor:	Mark C MacKinnon, Lorena Furlan, Gordon L. Lange
Rok vydání:	1998
Předmět:	chemistry.chemical_compound Fragmentation (mass spectrometry) Chemistry Stereochemistry Organic Chemistry Drug Discovery Biochemistry Cyclobutane
Zdroj:	Tetrahedron Letters. 39:5489-5492
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(98)01140-x
Popis:	A highly regio- and stereoselective synthesis of the sesquiterpenoid trichodiene is reported. The approach requires only nine steps starting with a [2+2] photoaddition and employs the free radical fragmentation of an “external” cyclobutane bond in a key step.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d95b2f29ae57cf3d6ef9e985e4a461d5 https://doi.org/10.1016/s0040-4039(98)01140-x Zobrazit plný text záznamu Full Text from ScienceDirect