Base-Promoted Regioselective Bromination of Imidazo[1,2-α]pyridines with CBr4 as Bromine Source
| Autor: | Fengmei Zhang, Pei He, Chunbo Liu, Qinpeng Shen, Jianjun Xia, Ying Han, Wen Xiong, Zhenjie Li, Shiyun Tang, Zhihua Liu |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Letters in Organic Chemistry. 20:72-76 |
| ISSN: | 1570-1786 |
| Popis: | Abstract: A bromination of hydrocarbons with CBr4 as a bromine source, promoted by NaOH, has been developed. The reaction method with high efficiency and regioselectivity for the synthesis of C3-brominated imidazo[1,2-α]pyridines. An effective and simple method of C-X bond construction has been developed, which is a supplement to the halide of imidazo[1,2-α]pyridines. |
| Databáze: | OpenAIRE |
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