CD68+ M1 MACROPHAGES IS ASSOCIATED WITH PLACENTAL INSUFFICIENCY UNDER FETAL GROWTH RESTRICTION
| Autor: | T. Mamontova, Antonina M Gromova, Varvara A Berezhna |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
CD68 business.industry Gestational age General Medicine Intervillous space Gestation period Placental insufficiency medicine.disease Andrology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure Placenta medicine Gestation Term Birth business 030215 immunology |
| Zdroj: | Wiadomości Lekarskie. 74:213-219 |
| ISSN: | 0043-5147 |
| DOI: | 10.36740/wlek202102107 |
| Popis: | OBJECTIVE The aim: To elucidate the possible involvement of M1 and M2 macrophages in the placentas of women, whose pregnancies were complicated by fetal growth restriction (FGR) and resulted in term births after 37 weeks of gestation and preterm births up to 37 weeks of gestation. PATIENTS AND METHODS Materials and methods: CD68+ and CD163+ macrophages were studied by immunohistochemical method, placental morphology in the placentas of 16 women whose pregnancies were complicated by FGR and resulted in term births at a gestational age after 37 weeks (1-st group, n = 7) or resulted in preterm births at a gestational age up to 37 weeks (2-nd group, n = 9). The control group consisted of 10 placentas of women with physiological pregnancies and births. RESULTS Results: Women 2-nd group showed significantly low weight of the placenta, a short gestation period at the time of delivery, and a prolonged labor period than women of the control group (p |
| Databáze: | OpenAIRE |
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