Secretory-IgA binding to intestinal microbiota attenuates inflammatory reactions as the intestinal barrier of preterm infants matures

Autor:	Sarah M Mahdally, Mariana Izquierdo, Rose M Viscardi, Laurence S Magder, Helena M Crowley, Andrea C Bafford, Cinthia B Drachenberg, Mauricio J Farfan, Alessio Fasano, Marcelo B Sztein, Rosangela Salerno-Goncalves
Rok vydání:	2023
Předmět:	Immunology Immunology and Allergy
Zdroj:	Clinical and Experimental Immunology.
ISSN:	1365-2249 0009-9104
Popis:	Previous work has shown that Secretory-IgA (SIgA) binding to the intestinal microbiota is variable and may regulate host inflammatory bowel responses. Nevertheless, the impact of the SIgA functional binding to the microbiota remains largely unknown in preterm infants whose immature epithelial barriers make them particularly susceptible to inflammation. Here, we investigated SIgA binding to intestinal microbiota isolated from stools of preterm infants
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d92f9e784e3816ca85f2bfe12b285db2 https://doi.org/10.1093/cei/uxad042 Zobrazit plný text záznamu