Transplacental carcinogenic action of p-hydroxyphenyllactic acid

Autor:	Zharova Ei, Sergeeva Ti, N. V. Makhalova, N. G. Chitiridi, Romanenko Vi, Raushenbakh Mo
Rok vydání:	1979
Předmět:	Pathology medicine.medical_specialty Lung Metabolite Transplacental General Medicine General Biochemistry Genetics and Molecular Biology stomatognathic diseases chemistry.chemical_compound medicine.anatomical_structure chemistry medicine Tyrosine Benign neoplasms Carcinogen
Zdroj:	Bulletin of Experimental Biology and Medicine. 87:46-48
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00802350
Popis:	Through the transplacental action of the tyrosine metabolite p-hydroxyphenyllactic acid, which has carcinogenic activity, on progeny of CC57BR and C57BL mice, malignant and benign neoplasms (leukemias, lymphosarcomas, adenomas and carcinomas of the lung, hepatomas, papillomas, carcinomas of the bladder, and other tumors) developed in 88 and 78% of cases respectively. The number of these neoplasms was significantly higher than in the control, they appeared sooner, and they were more malignant in character.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d9069485b3feaedf5e223569b64c690b https://doi.org/10.1007/bf00802350 Zobrazit plný text záznamu Full text from SpringerLink