Isocyanide-based three component reaction for synthesis of highly cyano substituted furan derivatives
| Autor: | Hamid Reza Safaei, Farbod Dehbozorgi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry General Chemical Engineering Aryl Isocyanide General Chemistry Carbon-13 NMR 010402 general chemistry Condensation reaction 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Furan Yield (chemistry) Proton NMR Organic chemistry Alkyl |
| Zdroj: | RSC Advances. 6:26783-26790 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/c5ra22293a |
| Popis: | A rapid and efficient solvent-free one-pot synthesis of novel alkyl amino aryl furan tricarbonitrile derivatives is described under catalyst-free conditions. This reaction was carried out through a three-component condensation reaction of isocyanides, 2-arylidenemalononitriles and benzoyl cyanide under solvent-free conditions. Neat conditions were established with many advantages, including high yield, environmentally friendliness, and easy and quick isolation of the products. The newly synthesized compounds were systematically characterized by IR, 1H NMR, 13C NMR and elemental analysis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|