Persistent headache after infection with the new coronavirus (COVID- 19): A Systematic Review

Autor: Samyla Coutinho Paniago, Caio de Almeida Lellis, Priscila Arantes e Silva Pereira, Camila de Assunção Martins, Sara Raquel Souza Silva, Ledismar José da Silva
Rok vydání: 2021
Zdroj: São Paulo Medical Journal.
DOI: 10.5327/1516-3180.061
Popis: Introduction: The new evidence has shown that infection with the new coronavirus is responsible for a series of neurological sequelae, which can persist even after the patient’s recovery, with headache being one of them. Objective: To assess the current evidence on the persistent headache after the infection with the new coronavirus. Design and setting: A systematic review conducted at the Pontifical Catholic University of Goiás. Methods: Systematic review. After filtering the duplicate studies and reading the title, abstract and full text of the remaining articles, studies that did not meet the objectives were excluded. Results: After the infiltration of the virus in the Central Nervous System, it can be observed that systemic disturbances occur, which lead to headaches with mild to intense intensity, with sudden and bilateral onset and frontotemporal localization being its most frequent presentation. Patients with a previous history of migraine were more susceptible to headache during COVID-19 infection, noting differences in the form of manifestation. In addition, several studies have concluded that this symptom can persist for more than 80 days and predispose to chronic headache. Conclusion: In view of the analysis of the articles exposed in this study, we can infer that headache is present as a clinical manifestation of great importance in cases of infection with the new coronavirus, and future multicenter randomized studies may clarify the possibility of a chronification of this symptom after this disease.
Databáze: OpenAIRE