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Introduction: Metabolic syndrome is believed to increase the risk of cardiovascular disease and postmenopausal women are more prone to develop cardiometabolic risk, most probably due to change in body fat distribution due to deciency of estrogen. Evidence regarding the clinical signicance of neck circumference in cardio-metabolic syndrome is limited. Also there is inconsistency in the results of studies regarding the relationship between neck circumference and lipid prole. Therefore, present study was conducted with an objective to examine association between neck circumference and lipid prole to nd the independent contribution of neck circumference to cardiometabolic risk. Materials and Methods: This was a hospital based cross-sectional, observational study. A total of 129 postmenopausal women, age > 45 years were selected consecutively after applying the inclusion and exclusion criteria. Anthropometric and biochemical parameters taken in our study were height, weight, BMI, neck circumference, waist circumference, fasting blood glucose, lipid prole. Neck circumference >=34cm was considered as abnormal. Metabolic syndrome was dened based on (AHA/NHLBI+IDF) 2009 criteria. Me Result: an neck circumference was found to be 32.52 ± 2.67cm. 40% of total subjects had neck circumference >=34cms. NC was found to be signicantly associated with components of metabolic syndrome (p |