| Popis: |
Kawasaki disease (KD) causes inflammation in medium-sized muscular arteries throughout the body, including the coronary artery, and is thus classified as a systemic vasculitis syndrome. In this chapter we review the histopathology of noncardiac organs, with a focus on vascular lesions. The main histopathological characteristic of KD vasculitis is proliferative inflammation consisting of marked accumulation of monocytes/macrophages. Vasculitis throughout the body starts at disease onset, rapidly reaches an inflammatory peak, and then slowly subsides and heals with scarring. KD vasculitis is thus a monophasic inflammatory process. |
