Antigenotoxic and Antioxidant Activities of Fruit Extracts from (Tunisian) Pistacia Lentiscus
| Autor: | Ines Bouhlel, Aicha Neffati, A. Abdelwahed, R. Ben Ammar, Wissem Bhouri, Ines Skandrani, M. Ben Sghaier, Kamel Ghedira, Leila Chekir-Ghedira, Jihed Boubaker |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Antioxidant
biology Chemistry DPPH General Chemical Engineering medicine.medical_treatment Xanthine biology.organism_classification medicine.disease_cause Industrial and Manufacturing Engineering SOS chromotest chemistry.chemical_compound Biochemistry Pistacia lentiscus medicine Food science Xanthine oxidase Genotoxicity Food Science Nifuroxazide medicine.drug |
| Zdroj: | Food Science and Technology International. 15:215-222 |
| ISSN: | 1532-1738 1082-0132 |
| DOI: | 10.1177/1082013208339705 |
| Popis: | Genotoxic and antigenotoxic activities against direct acting mutagen nifuroxazide, and indirect acting genotoxin aflatoxine B1 (AFB1) of extracts prepared from fruits of Pistacia lentiscus, were studied using the SOS chromotest with Escherichia coli PQ 37 as a tester organism. It was found that different extracts showed no genotoxicity when tested with E. coli PQ 37 strain either with or without microsomal extract. On the other hand, our results showed that ethyl acetate fraction and total oligomers flavonoids (TOF) extract obtained from P. lentiscus significantly decreased the genotoxicicity induced by AFB1 (10 μg/assay) and nifuroxazide (20 μg/assay). In addition to antigenotoxic activity, these extracts showed an important free radical scavenging activity towards the 2,2-diphenyl-2-picrylhydrazyl (DPPH) free radical and an important antioxidant activity using xanthine/xanthine oxidase system. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|