The Neuropharmacology of L-Theanine(N-Ethyl-L-Glutamine)

Autor:	Kristy Lu, Chris Oliver, Pradeep J. Nathan, Marcus A. Gray
Rok vydání:	2006
Předmět:	Pharmacology chemistry.chemical_compound chemistry Glutamate receptor NMDA receptor Kainate receptor Serotonin AMPA receptor Theanine Biochemistry Neuroprotection Neuropharmacology
Zdroj:	Journal of Herbal Pharmacotherapy. 6:21-30
ISSN:	1522-9106 1522-8940
DOI:	10.1080/j157v06n02_02
Popis:	L-theanine (N-ethyl-L-glutamine) or theanine is a major amino acid uniquely found in green tea. L-theanine has been historically reported as a relaxing agent, prompting scientific research on its pharmacology. Animal neurochemistry studies suggest that L-theanine increases brain serotonin, dopamine, GABA levels and has micromolar affinities for AMPA, Kainate and NMDA receptors. In addition has been shown to exert neuroprotective effects in animal models possibly through its antagonistic effects on group 1 metabotrophic glutamate receptors. Behavioural studies in animals suggest improvement in learning and memory. Overall, L-theanine displays a neuropharmacology suggestive of a possible neuroprotective and cognitive enhancing agent and warrants further investigation in animals and humans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d8ca646d7310aacdc81399c16e71b035 https://doi.org/10.1080/j157v06n02_02 Zobrazit plný text záznamu