Abstract PR-06: Examining disparities in incidence of colorectal cancer by race, ethnicity, sex, and site
| Autor: | Andrea Joyce M Malabay, Kristin Primm, Taylor Curry, Shine Chang |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Cancer Epidemiology, Biomarkers & Prevention. 31:PR-06 |
| ISSN: | 1538-7755 1055-9965 |
| DOI: | 10.1158/1538-7755.disp21-pr-06 |
| Popis: | Over the past 21 years, while the incidence of colorectal cancer in the US has decreased, disparities in race and ethnicity have increased but no recent evaluation exists of differences in race and ethnicity by location of primary tumors within the colon and rectum among all age groups. Recent literature has shown that there are differences in the rates of colorectal cancer between multiple minority groups; however, many of these studies only compare CRC among White and Black groups. We examined the trends of colorectal cancer incidence by racial/ethnic group and location of the primary tumors within the colon and rectum to describe disparities. This study used SEER*Stat v 8.3.9 Incidence – SEER Research Data, 18 Registries, Nov 2020 Sub (2000-2018) to analyze age-adjusted rates in incidence by race, ethnicity, sex, and site. We examined the sites within the proximal, transverse, and distal colon, as well as the rectum, and further examined localized, regional, and distant diagnosis stages. As others have reported, we observed declining incidence in colorectal cancer, but found that some racial and ethnic groups experienced higher incidence rates compared to other groups by diagnosis site and the stage of diagnosis. For example, when singling out the proximal colon, Black males had a rate of 12.7/100,000 people at the local stage in 2000. Comparing this localized proximal rate to male Whites (11.7), American Indian/Alaskan Natives (7.2), Asians/Pacific Islanders (6.9), and Hispanics (7.9), we can see that Blacks have already experienced a higher diagnosis rate than other races and ethnicities. Examining annual percent changes, incidence rates for Blacks decreased just as those for other racial and ethnic groups did. However, they do not experience the largest annual percent decrease. From this portion of the data, we see that some racial and ethnic groups had decreases in incidence trends. However, when examining each rate individually by subsite and diagnosis stage, some groups are seeing a trend where the rate is not as favorable. Despite declining incidence rates of colorectal cancer in the United States overall, comparisons by race and ethnicity reveal important disparities, particularly by site of primary tumors within the colon and rectum, which may have critical implications for treatment and long-term survival. Citation Format: Andrea Joyce M Malabay, Kristin Primm, Taylor Curry, Shine Chang. Examining disparities in incidence of colorectal cancer by race, ethnicity, sex, and site [abstract]. In: Proceedings of the AACR Virtual Conference: 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2021 Oct 6-8. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr PR-06. |
| Databáze: | OpenAIRE |
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